Director, Program Managment

Company: Alumis Inc.
Location: South San Francisco
Posted on: January 19, 2026

Job Description:

Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients. Alumis Inc is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer – our goal is to fundamentally change the outcomes for these patients. We are seeking an experienced and motivated Director, Program Management. In this highly visible, exciting role, you will partner with Project Team Leads and Project Team PMs (PT PMs) on molecule development teams, providing exceptional program management for our development molecules. This position will report to the Head of Program and Portfolio Management (PPM). RESPONSIBILITIES Actively partner with Project Team Leads (PTLs) and Project Team PMs, providing leadership and guidance for team and to team members Provide Project Management support by coordinating and aligning teams and associated workstreams, and managing their activities. This includes meeting facilitation, tracking of action items and team deliverables, to execute on program’s strategic plan and strategic objectives Partner with other PMs (Ex. Molecule PMs (supporting Project Team, Clinical Development teams, etc), CMC PM, Medical Affairs PM, Launch PM) to ensure seamless PPM support across molecules Ensure effective communication within functional team and stakeholders to support good decision-making in fast-paced small company environment Proactively identify, analyze and communicate decision points and project risks, including tradeoff and scenario analyses (including timelines, costs, and risks), framing options within broader molecule or portfolio context Identify needs and propose solutions to project and portfolio tools, systems and practices to support the growth and evolution of PPM’s capabilities As needed, provide Business Manager support including but not limited to driving annual business process execution (Ex. goals, budget, performance reviews), maintaining strong functional dynamics, acting as function lead or representative for enterprise-wide initiatives, and facilitating transparency and alignment with other functions and teams at Alumis As needed, act as a vendor liaison, providing contract, requisition processing, and invoice management support, as well as following up with vendor on project updates and status reports, to ensure timely and quality deliverables As needed, support other business priorities within PPM, including but not limited to potential assignments in research, development, clinical, launch, medical affairs, or CMC project management As needed, manage others THE IDEAL CANDIDATE Minimum 12 years industry experience, with at least 5 years of drug development project management (e.g. research, clinical, CMC, commercial, medical affairs), including clinical development project management experience Experience with filing and launch for small molecules Highly skilled in communication, stakeholder management, and influencing without authority, where you are able to effectively interact with, and facilitate complex conversations across the organization Excellent critical thinking, verbal and written communication skills, with ability to simplify and integrate multiple cross-functional perspectives and inputs for team Agile and flexible: Able to step in, assess situations, and help team to make sound decisions in alignment with program strategy Strong organizational skills with critical attention to detail and ability to track to numerous deliverables Broad scientific and business acumen in the biotech or pharmaceutical industry, including a strong understanding of cross-functional dependencies Proficient with Microsoft Office Suite, as well as project management software such as MS Project and Smartsheets EDUCATION A. or BSc. with MSc., MBA or Ph.D. a plus Project Management Professional (PMP) or other PM certification a plus The salary range for this position is $197,000 USD to $247,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices. This position is located in South San Francisco, CA, with an expectation to be onsite Tuesday through Thursday. Alumis Inc. is an equal opportunity employer. Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program. Other benefits include: Health insurance premiums paid at 90% for employee, 80% for dependents Free access to Genentech Bus & Ferry Share program $100 monthly cell phone stipend Unlimited PTO for Exempt employees Free onsite gym and a kitchen stocked with yummy snacks and drinks! We are a hard-working, collaborative team on a mission to transform patient’s lives and we aspire to elevate , challenge and nurture one another along the way.

Keywords: Alumis Inc., Santa Cruz , Director, Program Managment, Science, Research & Development , South San Francisco, California