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Scientist I/II Cancer Cell Biology

Company: Unnatural Products Inc.
Location: Santa Cruz
Posted on: January 7, 2022

Job Description:

About the Company: -Unnatural Products Inc. (UNP) is a VC-backed drug discovery company committed to tackling some of oncology's toughest challenges, drug targets previously deemed "undruggable." UNP uses both computational and empirical techniques to create a next-generation drug modality - cell-permeable, cyclic peptides. We have multiple partnerships with top-tier pharma customers as well as a growing internal pipeline driven by our platform.
U.S. Work Authorization Required. -Role SummaryThe Scientist will be an integral member of the UNP Biology Team. The Biology team identifies and validates molecular targets, evaluates novel drug candidates, and provides forward-thinking approaches to advance our preclinical pipeline. The Scientist will independently design and conduct cellular assays, determine the efficacy and mechanism of action of macrocyclic inhibitors, and conduct experiments that validate potential targets. This is a hands-on position for an experienced wet-lab scientist who enjoys working at the bench. The Scientist must have excellent communication skills and work with a positive attitude in a dynamic, fast-paced, cross-functional team environment. -Job Responsibilities:--- - - - - - - -Create, develop and validate quantitative cell-based assays to address mechanistic and functional needs for pipeline projects and platform--- - - - - - - -Plan and manage assay work-flows across multiple projects--- - - - - - - -Design, execute and analyze experiments--- - - - - - - -Train and mentor junior members of the organization--- - - - - - - -When necessary, lead and support troubleshooting activities to achieve project aims.--- - - - - - - -Directly interact and update the project progress with the team--- - - - - - - -Learn new scientific skills as required by pipeline projects -Qualifications:--- - - - - - - -PhD in Molecular/Cellular Biology or Biochemistry, or related field with 0-2 years of postdoctoral research experience or BS/MS in Molecular/Cellular Biology or Biochemistry or related disciplines with 7+ years work experience in a biotech/pharma setting--- - - - - - - -Strong understanding of cancer biology and signal pathways --- - - - - - - -Demonstrated extensive experience in mammalian cell culture; creating, developing and running cellular assays, and interrogating biological pathways using chemical biology tools--- - - - - - - -Strongly preferred skills include cell-line engineering using CRISPR to create knock-out or knock-in of our genes of interest--- - - - - - - -Experience with general molecular biological techniques including molecular cloning, qPCR, ELISA, proximity-based assays, immunoprecipitations, Western blotting.--- - - - - - - -Excellent interpersonal skills with ability to communicate and interact well with colleagues, vendors, CROs, and scientific advisors--- - - - - - - -Highly organized with excellent analytical, documentation and multi-tasking skills--- - - - - - - -Enthusiastic, self-motivated individual excited -to work in the fast-paced and dynamic environment of a startup -Perks:UNP employees enjoy numerous benefits including full healthcare coverage, 401k with employer contribution, flexible time off, continuing education stipends, weekly team lunches, charity matching, and more. Our offices and lab space is located in Santa Cruz, CA, and we are a short walk to the beach with world class surf or a hike in the beautiful redwoods. We are looking for people to join our team who share our passion for rigorous science, best practices engineering, and working in a fun, fast paced, and inclusive environment. -Unnatural Products Inc. is a committed equal opportunity employer and evaluates job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability, or veteran status.

Keywords: Unnatural Products Inc., Santa Cruz , Scientist I/II Cancer Cell Biology, Other , Santa Cruz, California

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